In cases of acute intoxication with propane butane (due to damage in heating appliances where propane-butane is used as energy source for heating), asphyxia. Butane is an organic compound with the formula C4H10 that is an alkane with four carbon . It enters the blood supply and within seconds produces intoxication. Butane is the most commonly misused volatile substance in the UK, and was the. Butane is a commonly misused volatile agent, and a cause of intoxication. We present a case, who had a syncope and persistent ventricular.
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The chamber concentration was periodically analyzed. Cardiopulmonary resuscitation was commenced. Also, no noticeable irritation was reported at concentrations up toppm butame for a few minand a larger uncertainty factor of 3 would lead to unrealistically low AEGL-1 values. Butane is a hydrocarbon, found in household and industrial products and is potentially intoxicating if deliberately inhaled.
The number of animals was not specified but the results suggest that exposure groups consisted of 6 animals. American Journal of Applied Sciences. Our online ‘Live Help’ chat service offers you a person to talk to. Odor detection was rated by means of an odor scale ranging from 0 no detectable odor to 5 intense effect, may bite or irritate.
A species with a relatively high susceptibility is used as starting point.
Retrieved from ” https: An ultrasound at week 39 of the pregnancy showed an almost complete absence of brain tissue in the fetus. Butane is also used as lighter fuel for a common lighter or butane torch and is sold bottled as a fuel for cooking, barbecues and camping stoves.
Withdrawal symptoms can continue for a number of days when use ceases. Although the reduction in concentration can be regarded as negligible for short-exposure durations because of general variation in actual exposure concentrations, a mean exposure duration of 1 min is inadequate as starting point for time scaling to 8 h of exposure.
Subjects first underwent the continuous exposure test, followed on the same day by the intermittent exposure test after a recovery period. The calculated 2-h LC 01 isppm. This article has been cited by 1 Fatal poisoning by butane sniffing: Retrieved 11 December Handbook of Chemistry and Physics. Neurotoxicity No data other than that described in Sections 3.
An indication for the value of n for CNS-depressing effects can be obtained from the study by Stoughton and Lamson Clin Toxicol Phila ; Cardiopulmonary resuscitation was needed. LC 16 ratio was 1.
Butane intoxication–three case reports.
Further, brain concentrations of butane in dead mice and rats exposed at the LC 50 appeared to be comparable. No adequate human data relevant to AEGL-2 effects were found.
One guinea pig exposed for 2 h was examined histopathologically 7 days after exposure; no effects were found. Sudden cardiac death and substance abuse; pp. The response in mice and rats were remarkably comparable at similar concentrations, despite the difference in exposure duration. The relationship between concentration and duration of exposure as related to lethality was examined by ten Berge et al.
Butane sniffing causing ventricular fibrillation; p.
If the person gets excited, startled or participates in any sudden physical activity after inhaling intoixcation, the heart can fail to pump blood. No increase in the severity of response by duration is expected for concentration-dependent effects after reaching a steady state.
Retrieved 3 October Airborne concentrations below the AEGL-1 represent exposure concentrations that could produce mild and progressively increasing but transient and nondisabling odor, taste, and sensory irritation or certain asymptomatic, nonsensory effects.
Although a table in the report indicated that exposure to butane at 10, ppm for 10 min caused drowsiness, this was contradicted by a statement in the text that min exposure to butane 10, ppm caused no symptoms. No deaths occurred in mice exposed for 2 h atorppm. A CT scan showed a very tight swollen brain. A year-old girl without a history of butane abuse inhaled butane intermittently over a 2-h period.
Butane intoxication–three case reports.
Rats Shugaev exposed rats sex and strain not specified to varying concentrations of butane for 4 h. Some data are available on cardiac effects in dogs, but they are insufficient for setting AEGL values. Exposure concentrations were reported to be controlled by gas chromatography, but no intoxicatiob about the concentrations of butane tested or the duration of the post-exposure observation period was provided.